{"id":1043,"date":"2024-04-30T13:43:58","date_gmt":"2024-04-30T10:43:58","guid":{"rendered":"https:\/\/sulfostrength.com\/?page_id=1043"},"modified":"2024-06-06T14:45:12","modified_gmt":"2024-06-06T11:45:12","slug":"mechanisms-of-action-gr","status":"publish","type":"page","link":"https:\/\/sulfostrength.com\/index.php\/el\/mechanisms-of-action-gr\/","title":{"rendered":"\u039c\u0397\u03a7\u0391\u039d\u0399\u03a3\u039c\u039f\u0399 \u0394\u03a1\u0391\u03a3\u0397\u03a3"},"content":{"rendered":"\n

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\u039f\u0399 \u03a5\u03a0\u0395\u03a1\u0394\u03a5\u039d\u0391\u039c\u0395\u0399\u03a3 \u03a4\u0397\u03a3 \u03a3\u039f\u03a5\u039b\u03a6\u039f\u03a1\u0391\u03a6\u0391\u039d\u0397\u03a3<\/strong><\/p>\n\n\n\n

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\u0391\u039d\u03a4\u0399\u039f\u039e\u0395\u0399\u0394\u03a9\u03a4\u0399\u039a\u0397 \u0394\u03a1\u0391\u03a3\u0397<\/mark><\/strong><\/p>\n\n\n\n

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\u03a0\u03b7\u03b3\u03ad\u03c2<\/strong><\/summary>\n

Boddupalli et al., 2012 : \u201cInduction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins A, C, and E\u201d Review<\/mark> Link<\/a> <\/p>\n\n\n\n

Houghton et al., 2016 : \u00ab Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician\u2019s Expectation Be Matched by the Reality?\u201d Link<\/a> <\/p>\n\n\n\n

Kubo et al., 2017 : \u201cSulforaphane reactivates cellular antioxidant defense by inducing Nrf2\/ARE\/Prdx6 activity during aging and oxidative stress\u201d in vitro Link<\/a> <\/p>\n\n\n\n

Alrawaiq et al., 2023 : \u201c Effect of Administration of an Equal Dose of Selected Dietary Chemicals on Nrf2 Nuclear Translocation in the Mouse Liver\u201d in vivo Link<\/a><\/mark><\/p>\n<\/details>\n<\/div>\n\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

\u0391\u039d\u03a4\u0399\u03a6\u039b\u0395\u0393\u039c\u039f\u039d\u03a9\u0394\u0397\u03a3 \u0394\u03a1\u0391\u03a3\u0397<\/strong><\/p>\n\n\n\n

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\u03a0\u03b7\u03b3\u03ad\u03c2<\/strong><\/summary>\n

Thejass P, Kuttan G. Immunomodulatory activity of Sulforaphane, a naturally occurring isothiocyanate from broccoli (Brassica oleracea). Phytomedicine. 2007 Aug;14(7-8):538-45. doi: 10.1016\/j.phymed.2006.09.013. Epub 2006 Nov 3. PMID: 17084602. Link<\/a><\/p>\n\n\n\n

Ahmed SM, Luo L, Namani A, Wang XJ, Tang X. Nrf2 signaling pathway: Pivotal roles in inflammation. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):585-597. doi: 10.1016\/j.bbadis.2016.11.005. Epub 2016 Nov 4. PMID: 27825853. Link<\/a><\/p>\n\n\n\n

Ruhee RT, Suzuki K. The Integrative Role of Sulforaphane in Preventing Inflammation, Oxidative Stress and Fatigue: A Review of a Potential Protective Phytochemical. Antioxidants (Basel). 2020 Jun 13;9(6):521. doi: 10.3390\/antiox9060521. PMID: 32545803; PMCID: PMC7346151. Link<\/a><\/p>\n<\/details>\n<\/div>\n\n\n\n

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\u039a\u03a5\u03a4\u03a4\u0391\u03a1\u0399\u039a\u0397 \u03a0\u03a1\u039f\u03a3\u03a4\u0391\u03a3\u0399\u0391<\/mark><\/strong><\/p>\n\n\n\n

\u0397 \u03c3\u03bf\u03c5\u03bb\u03c6\u03bf\u03c1\u03b1\u03c6\u03ac\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03cc\u03c4\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03ad\u03bd\u03b1<\/mark> \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd. \u039c\u03c0\u03bb\u03bf\u03ba\u03ac\u03c1\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03b9\u03c3\u03c4\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03bf\u03b1\u03ba\u03b5\u03c4\u03c5\u03bb\u03ac\u03c3\u03b5\u03c2 (HDAC), \u03ad\u03bd\u03b1 \u03ad\u03bd\u03b6\u03c5\u03bc\u03bf \u03c0\u03bf\u03c5 \u03b5\u03bb\u03ad\u03b3\u03c7\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd, \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ad\u03c4\u03c3\u03b9 \u03c4\u03b7\u03bd \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03bf\u03c5.<\/mark><\/p>\n\n\n\n

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\u03a0\u03b7\u03b3\u03ad\u03c2<\/strong><\/summary>\n

Houghton CA. Sulforaphane: Its „Coming of Age“ as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxid Med Cell Longev. 2019 Oct 14;2019:2716870. doi: 10.1155\/2019\/2716870. PMID: 31737167; PMCID: PMC6815645. Link<\/a><\/p>\n\n\n\n

Kaufman-Szymczyk A, Majewski G, Lubecka-Pietruszewska K, Fabianowska-Majewska K. The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation. Int J Mol Sci. 2015 Dec 12;16(12):29732-43. doi: 10.3390\/ijms161226195. PMID: 26703571; PMCID: PMC4691138. Link<\/a><\/p>\n<\/details>\n<\/div>\n\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

\u03a6\u03a1\u039f\u039d\u03a4\u0399\u0396\u0395\u0399 \u0393\u0399\u0391 \u03a4\u0391 \u03a0\u03a1\u03a9\u03a4\u0391 \u03a3\u0397\u039c\u0391\u0394\u0399\u0391 \u03a6\u03a5\u03a3\u0399\u039f\u039b\u039f\u0393\u0399\u039a\u0397\u03a3 \u0393\u0397\u03a1\u0391\u039d\u03a3\u0397\u03a3 \u03a4\u039f\u03a5 \u03a0\u03a1\u039f\u03a3\u03a4\u0391\u03a4\u0397<\/strong><\/p>\n\n\n\n

\u03a4\u03bf Prostaphane\u00ae \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c3\u03c9\u03c3\u03c4\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7. \u0397 \u03c3\u03bf\u03c5\u03bb\u03c6\u03bf\u03c1\u03b1\u03c6\u03ac\u03bd\u03b7 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c0\u03b9\u03bf \u03b9\u03c3\u03c7\u03c5\u03c1\u03ad\u03c2 \u03c6\u03c5\u03c3\u03b9\u03ba\u03ad\u03c2 \u03bf\u03c5\u03c3\u03af\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c3\u03c9\u03c3\u03c4\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7.<\/p>\n\n\n\n

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\u03a0\u03b7\u03b3\u03ad\u03c2<\/strong>
<\/summary>\n

Mordecai J, Ullah S, Ahmad I. Sulforaphane and Its Protective Role in Prostate Cancer: A Mechanistic Approach. Int J Mol Sci. 2023 Apr 10;24(8):6979. doi: 10.3390\/ijms24086979. PMID: 37108142; PMCID: PMC10138336. Link<\/a><\/p>\n\n\n\n

Shivendra V. Singh, Sanjay K. Srivastava, Sunga Choi, Karen L. Lew, Jedrzej Antosiewicz, Dong Xiao, Yan Zeng, Simon C. Watkins, Candace S. Johnson, Donald L. Trump, Yong J. Lee, Hui Xiao, Anna Herman-Antosiewicz,
Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species*, Journal of Biological Chemistry, Volume 280, Issue 20,
2005 Link<\/a><\/p>\n\n\n\n

Livingstone TL, Saha S, Bernuzzi F, Savva GM, Troncoso-Rey P, Traka MH, Mills RD, Ball RY, Mithen RF. Accumulation of Sulforaphane and Alliin in Human Prostate Tissue. Nutrients. 2022 Aug 10;14(16):3263. doi: 10.3390\/nu14163263. PMID: 36014767; PMCID: PMC9415180. Link<\/a><\/p>\n\n\n\n

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